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. Author manuscript; available in PMC: 2022 Aug 29.
Published in final edited form as: Br J Nutr. 2010 Dec;104(11):1586–1600. doi: 10.1017/S0007114510004010

Table 4.

Fatty acid composition of ‘n-6 specific PUFA’, ‘mixed’ and ‘n-3 specific PUFA’ oils used in randomised controlled trials*

Oil LA ALA EPA + DHA Total SFA Cholesterol reduction (mg/dl per tbsp)
n-6 specific PUFA
 Safflower 74·6 0·0 6·2 −28§
 Corn 53·5 1·2 12·9 −25
Mixed (n-6 + n-3 PUFA)
 Soybean 50·3 7·0 15·3 −11
n-3 specific PUFA
 Cod liver 0·9 0·9 17·9 22·6

LA, linoleic acid; ALA, α-linolenic acid; tbsp, table spoon.

*

Fatty acid composition values from United States Department of Agriculture National Nutrient Database for Standard Reference, Release 22. Nutrient Data-bank Identifier numbers (NDB) are as follows: Safflower, 04 510; Corn, 04 510; Soybean, 04 669; Cod liver, 04 589.

Data are expressed in g/100 g

Based on a predictive model for lowering serum cholesterol developed by Ancel Keys and University of Minnesota collaborators, using data from Hastings and Faribault Mental Hospitals and the National Diet Heart Study.

§

Safflower oil has the most potent cholesterol-lowering effect of any vegetable or seed oil.

Corn oil, which is rich in phytosterols that enhance its cholesterol-lowering effect(92), is the second most potent cholesterol-lowering oil.