Table 4.

Factors Contributing to the 10-2 VF Loss Progression Assessed by clustered PLR in Study Participants using Univariable and Multivariable Logistic Regression Analyses.

Variables	Univariate Model		Multivariable Model I		Multivariable Model II
	Odds ratio, 95% CI	P value	Odds ratio, 95 % CI	P value	Odds ratio, 95 % CI	P value
Age, per 10 year older	10.06 (9.70, 10.44)	0.732	10.17 (9.78, 10.57)	0.404	10.18 (9.79, 10.59)	0.377
Gender: M/F	0.99 (0.48, 2.02)	0.973
Race: African American/ Non-African American	1.38 (0.63, 3.00)	0.417
Axial length, per 1mm longer	1.05 (0.81, 1.36)	0.719
CCT, per 10 μm thinner	10.01 (9.93, 10.1)	0.749
Self-reported diabetes	1.39 (0.51, 3.83)	0.519
Self-reported hypertension	0.59 (0.28, 1.22)	0.153
MOPP, per 1 mmHg higher	1.01 (0.96, 1.06)	0.788
Baseline IOP, per 1 mmHg higher	1.01 (0.92, 1.10)	0.884
Mean IOP, per 1 mmHg higher	1.01 (0.91, 1.12)	0.899	1.05 (0.95, 1.17)	0.301	1.04 (0.93, 1.15)	0.512
History of disc hemorrhage	3.65 (1.58, 8.42)	0.002	3.78 (1.56, 9.13)	0.003	3.51 (1.48, 8.29)	0.004
Baseline MD 10-2, per 1 dB worse	1.04 ( 0.99, 1.09 )	0.096			1.05 ( 1, 1.11 )	0.074
Baseline MD 24-2, per 1 dB worse	1.06 ( 1.02, 1.11 )	0.004	1.08 ( 1.03, 1.13 )	0.002
Follow-up time, per 1 year longer	1.16 (0.98, 1.37)	0.088	1.17 (0.97, 1.40)	0.106	1.19 (0.97, 1.45)	0.096

CCT = central corneal thickness; F = female; IOP = intraocular pressure; M = male; MD = mean deviation; MOPP = mean ocular perfusion pressure; VF = visual field. Values are shown in odds ratio (95% confidence interval), unless otherwise indicated. Age, mean IOP and variables with a P value of less than 0.10 in the univariable analysis were included in the multivariable model. Statistically significant P values are shown in bold.