Table 5.
Meta-analysis estimates of cochlear implantation on the Tinnitus Handicap Inventory score. The mean summary difference across the studies indicated an 11.66-point reduction in the tinnitus severity score (95% CI 5.67 to 17.65; p < 0.001). There was marked heterogeneity between the studies (I2 = 96.4%).
| Study | Mean differences | 95% CI | Weight (%) |
|---|---|---|---|
| 1. Arts R.A. et al. | 12.50 | 8.16; 16.84 | 13.87 |
| 2. Arts R.A. et al. | 17.10 | 13.17; 21.03 | 14.06 |
| 3. Dillon M.T. et al. | 18.15 | 16.11; 20.19 | 14.71 |
| 4. Ramakers G.G.J. et al. 1 | -3.07 | -6.07; -0.06 | 14.42 |
| 5. Ramakers G.G.J. et al. 2 | 6.44 | 4.07; 8.82 | 14.62 |
| 6. Di Nardo W. et al. | 19.50 | 14.99; 24.01 | 13.79 |
| 7. van Zon A. et al. | 11.46 | 8.77; 14.15 | 14.53 |
| Global | 11.66 | 5.67; 17.65 | 100.00 |
Heterogeneity (p-value < 0.001); I2 = 96.4% of variation (randomized); global means test (p-value ≤ 0.001).