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. 2022 Aug 22;20(4):358–367. doi: 10.1089/lrb.2021.0031

FIG. 1.

FIG. 1.

Survival and chylous incidents in VD mice. (A) Survival curves for WT and VD mice provided 600 mg/kg doxycycline in their chow diet or HFD. (B) Images of chylous ascites (left) and chylothorax (right) identified at time of sacrifice. (C) Incidence of chylous events identified through 4 months of HFD feeding in VD mice. (D) Survival curves of VD mice provided 600 mg/kg doxycycline in 60% kcal from fat HFD enriched for unsaturated fat (HUSFD), standard mixed formulation (HFD), and high saturated fat (HSFD). (E) Incidence of chylous events identified through 4 months of HFD feeding in VD mice provided HUSFD (blue, left), HFD (black, center), or HSFD (red, right). HFD, high fat diet; HSFD, high saturated fat diet; HUSFD, high unsaturated fat diet; VD, vascular endothelial growth factor-D; WT, wildtype.