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. 2022 Aug 26;12(8):e057303. doi: 10.1136/bmjopen-2021-057303

Table 3.

Age-specific and sex-specific risks of suicide, suicidal attempts/ideation during use of methylphenidate

Characteristic Cases/controls
(n)
HR
(95% CI)
Women 64/44 043 3.9 (1.5 to 10.2)
Men 65/52 294 1.1 (0.4 to 2.6)
18–40 years of age 84/62 196 2.4 (1.2 to 4.9)
41–60 years of age 38/28 108 1.3 (0.4 to 4.9)
61–80 years of age 4/4543 1.6 (0.0 to ∞)
>80 years of age 3/836 –*

All hazard ratios (HR) are adjusted for sex, age, intervention, smoking, BMI, alcohol abuse, acute alcohol intoxication, medicines abuse, tobacco abuse, drug abuse, psychosis in history (for non-psychotic endpoints), depression in history (for non-depressive endpoints), anxiety in history (for non-anxiety endpoints), neuroses in history, personality disorder, other psychiatric disease and ‘intention-to-treat’.

*No cases exposed to methylphenidate.

BMI, body mass index.

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