Table 4.

Age-specific and sex-specific risks of al-cause mortality during the use of methylphenidate

Characteristic	Cases/controls (n)	HR (95% CI)
Women	375/44 077	1.7 (1.2 to 2.5)
Men	571/52 154	1.1 (0.8 to 1.5)
18–40 years of age	67/62 478	1.2 (0.4 to 3.5)
41–60 years of age	240/28 191	1.1 (0.7 to 1.8)
61–80 years of age	412/4781	1.6 (1.2 to 2.2)
>80 years of age	227/721	1.2 (0.7 to 2.0)

All HRs are adjusted for sex, age, smoking, hypertension, diabetes mellitus, BMI, hypercholesterolemia, decreased renal function and ‘intention-to-treat’

BMI, body mass index.