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Effect of ipragliflozin (Ipra), furosemide (Furo), or vehicle (Veh) on changes in food intake (A), fluid intake (B), urine volume (C), and fluid balance (D) on day 2 in nondiabetic Sprague-Dawley rats. Drug doses are as in Fig. 1. One-way ANOVA followed by a post hoc Tukey honestly significant difference test or Student’s t test were used for statistical analysis. Values are expressed as means ± SE; n = 23–30/group.
