Table 2.
Summarised parameters of cases of adenoid ameloblastoma with dentinoid
| Author and year of publication | Age in years | Gender | Duration | Arch | Side | Symptom | Radiographic feature | Histopathological feature | Special stains/IHC | Final diagnosis | Treatment (with number of recurrences) | Follow-up with NED |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Slabbert et al.6 (1992) | 24 | Male | N/P | Mn | Left | Swelling | UL RL | AM-F, AM-P, AOT-S, DM | Van Gieson + Masson’s trichrome + Congo red − Alcian blue − |
Dentinoame-loblastoma | WE | N/P |
| Matsumoto et al.8 (2001) | 19 | Male | 1 mo | Mn | Right | Swelling | WD UL RL | AM-P, AOT-S, AOT-D, DM | Mucicarmine + Alcian blue + |
Atypical plexiform AM with dentinoid | Marsupialisation + enucleation; (1 rec after 2 yr); WE | 2.5 yr |
| Evans et al.9 (2004) | 39 | Male | N/P | Mn | CM | Swelling | WD UL RL | AM-P, AOT-S, AOT-D, DM, CC | N/P | AM with features of AOT | WE; WE + curettage enucleation + curettage; (3 recs over a 16-yr period); SR | 18 mo |
| Zhang et al.10 (2006) | 64 | Female | 16 mo | Mn | CM | Swelling + paresthesia | WD UL RL with RO clusters | AM-F, AOT-S, AOT-R, DM, GC | N/P | Hybrid odontogenic tumor characteristic of CCOT, solid multicystic AM and AOT | SR | 3 yr |
| Jivan et al.12 (2007) | 40 | Male | 7 mo | Mn | CM | Swelling | WD UL RL | UAM, AOT-S, AOT-D, AOT-R, DM | Calretinin ++ in cystic lining | AOT originating within a unicystic AM | N/P | N/P |
| Ghasemi-Moridani et al.15 (2008) | 19 | Female | 2 mo | Mx | Right | Swelling | WD UL RL | AM-P, AOT-S, AOT-D, DM | N/P | AAD | Excision | N/P |
| Ide et al.16 (2009) | 44 | Male | N/P | Mx | CM | N/P | WD UL RL | AM-P, AOT-S, AOT-D, AOT4, DM | Calretinin + | AAD | En; Excision; (3 recs over a 11-year period) Partial maxillectomy | 8 yr |
| Sonone et al.17 (2011) | 35 | Female | 1 year | Mn | Right | Swelling + numbness | WD UL RL with RO foci | AM-P, AOT-S, AOT-D, AOT-R, DM, GC Congo red − |
Van Gieson + | AAD | SR | 6 mo |
| Saxena et al.18 (2012) | 45 | Male | 2 wk | Mx | Left | Swelling | Diffuse RL | AM-P, AM4 AOT-D, AOT-S, DM | N/P | AAD | WE (3 recs) SR | N/P |
| Yamazaki et al.11 (2014) | 31 | Female | N/P | Mn | Right | None | WD UL RL with sclerotic area in distal portion | AM-F, AM-P, AOT-S, AOT-D, DM, CC CK17 + Calretinin + Ki-67 + Congo red + |
CK19 ++ | Hybrid AM and AOT | SR | 36 mo |
| Loyola et al.13 (2015) | 55 | Male | 5 mo | Mn | Left | Swelling | N/P | AM-F, AM-P, AOT-S, AOT-D, DM | CK19: ++ Ki-67 ++ CK8/18 − |
AAD | 1 rec; SR | 108 mo |
| 24 | Female | 6 mo | Mx | Left | Swelling | WD UL RL | None | Adenoid AM (hybrid/ mixed odontogenic tumour) | WE | 6 mo | ||
| Loyola et al.13 (2015) | 31 | Male | 1 mo | Mn | Right | Swelling | WD RL | None | Adenoid granular cell AM with dentinoid | Hemimandibulectomy | 18 mo | |
| 40 | Male | N/P | Mn | CM | Swelling, numbness, parasthesia | WD UL RL | AM-F, AM-P, AOT-S, AOT-D, DM | Calretinin ++ p53 ++ |
Atypical adenoid AM | Hemimandibulectomy | 14 mo | |
| 16 | Female | 2 mo | Mn | Right | Swelling | UL RL | None | AAD | WE | 12 mo | ||
| Kumar et al.19 (2013) | 55 | Male | 3 mo | Mn | Right | Swelling, pain, paresthesia | WD UL RL | AM-P, AOT-S, AOT-D, AOT-R, DM, GC | CK19 + | AAD | SR | 36 mo |
| Salehinejad et al.20 (2016) | 34 | Female | 43 mo | Mx | Right | Swelling | PD RL | AM-F, AM-P, AOT-D, DM | CK19 ++ Ki-67 ++ CK8/18 + |
AAD | 9 recs; SR | 19 mo |
| Khalele et al.21 (2016) | 33 | Female | 48 mo | Mx | Right | Swelling + pain | N/P | AM-F, AM-P, AOT-S, AOT-D, AOT-R, DM | CK19 ++ Ki-67 ++ CK8/18 − |
AAD | 5 recs; SR + radiotherapy + neck dissection | N/P |
| Sathyanarayan et al.22 (2017) | 51 | Male | 72 mo | Mx | CM | Swelling + pain | PD RL | UAM, AOT-S, AOT-D, AOT-R, DM | CK19 ++ Ki-67 ++ CK8/18 + |
AAD | 5 recs; SR | 76 mo |
| Rai et al.23 (2017) | 47 | Male | 18 mo | Mx | CM | Swelling | N/P | AM-F, AOT-S, AOT-D, DM | CK19 ++ Ki-67 ++ CK8/18 + |
AAD | 2 recs; SR + radiotherapy + neck dissection | 52 mo |
| Adorno-Farias et al.24 (2018) | 15 | Female | 12 mo | Mn | N/P | Swelling | UL RL | AM-F, AOT-S, AOT-D, DM | CK7 − CK14 − CK19 + IMP3 − Ki-67 + p53 − |
AM with adenoid features | SR | N/P |
| 37 | Male | 12 mo | Mn | Left | Swelling + pain | WD ML RL | AM-F, AOT-S, AOT-D, DM, CC | CK7 − CK14 − CK19 ++ IMP3 − Ki-67 + p53 − |
SR | N/P | ||
| 46 | Female | N/P | Mn | N/P | N/P | UL RL | CK7 − CK14 − CK19 ++ IMP3 − Ki-67 + p53 − |
SR | N/P | |||
| Adorno-Farias et al.24 (2018) | 34 | Female | N/P | Mn | N/P | Swelling | UL RL | AM-F, AOT-S, AOT-D, DM, CC | CK7 − CK14 − CK19 + IMP3 − Ki-67 + p53 − |
AM with adenoid features | SR | N/P |
| N/P | Female | N/P | N/P | N/P | UL RL | CK7 − CK14 − CK19 ++ IMP3 − Ki-67 + p53 − |
SR | N/P | ||||
| 15 | Male | 12 mo | Mn | Swelling | UL RL | AM-F, AOT-S, AOT-D, DM, CC | CK7 − CK14 ++ CK19 ++ IMP3 − Ki-67 + p53 − |
SR | N/P | |||
| 82 | Male | 36 mo | Mn | Swelling | ML RL | AM-F, AOT-D, DM, CC, GC | CK7 − CK14 ++ CK19 ++ IMP3 − Ki-67 + p53 − |
SR | N/P | |||
| 46 | Male | N/P | N/P | N/P | UL RL | AM-F, AOT-D, DM, CC | CK7 − CK14 ++ CK19 + IMP3 − Ki-67 + p53 − |
SR | N/P | |||
| Arruda et al.25 (2020) | 51 | Female | N/P | Mx | Left | None | WD UL RL | AM-P, AOT-S, AOT-D, DM | Alcian blue | AAD | 1 rec; SR | 108 mo |
N/P = not provided; Mn = mandible; Mx = maxilla; CM = crossing midline; WD = well-defined; PD = poorly defined; UL = unilocular; ML = multilocular; RL = radiolucency; RO = radiopaque; WE = wide excision; SR = surgical resection; Rec = recurrence.