Fig. 4.

Effects of micro ribonucleic acid (miR)-124a on messenger ribonucleic acid (mRNA) and protein expression levels of related factors in the Notch pathway in rat myocardial tissue after ischemia reperfusion (I/R). (A) mRNA expression levels of miR-124a, BAX, and nuclear factor kappa B (NF-κB) in each group. (B) mRNA expression levels of Notch1 and Hes1 in each group. (C) Western blot was used to detect the protein expression levels of BAX, NF-κB, Notch1, and Hes1 in the myocardial tissues of each group. (D) Protein expression levels of BAX, NF-κB, Notch1, and Hes1 in the myocardial tissues of each group. The values are expressed as X±S. Compared with sham group, *P<0.05; compared with I/R group, #P<0.05. ant=antagomir; GAPDH=glyceraldehyde 3-phosphate dehydrogenase; NC=normal control