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. 2021 Feb 8;17(8):819–836. doi: 10.1080/15592294.2021.1876297

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Figure 4. — Association between MSI2, RAPH1 and SLC25A10 DNA methylation with inflammation and adipokines at age 17-years.

Linear regression models between DNA methylation levels at pyrosequenced CpGs (MSI2, SLC25A10, RAPH1) on the outcomes of hsCRP, leptin and adiponectin. Beta coefficient and 95% CI are shown, adjusted for age, sex, cell count and for me-QTL SNP, where identified by GEM package [44]. All β-coefficients are expressed per SD change of CpG. ^For SLC25A10, the relevant me-QTL is rs6565624 using the additive model.