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. 2021 Feb 8;17(8):819–836. doi: 10.1080/15592294.2021.1876297

Table 3.

Final linear regression model predicting BMI at 17 years old. Linear regression model for the outcome of BMI at 17-years was formed by backward selection with pre-pregnancy BMI, maternal smoking at 18-weeks gestation and GWG, all pyrosequenced CpGs, cell counts and potential me-QTLs (rs6565624_G, rs3830068_G, rs12452184_A). The model (r2 = 0.243 (SE = 0.15), includes independent effects of rs6565624_G, MSI2 CpG1, RAPH1, maternal smoking at 18-weeks, pre-pregnancy BMI, CD8+, CD4 + T cells, and granulocytes.

Parameter Beta SE Sig.
rs6565624_G 0.043 0.012 3.8 x 10−4
RAPH1 (Z score) 0.088 0.020 8.4 x 10 −6
MSI2 CpG1 (Z score) 0.021 0.009 0.022
Maternal smoking at 18 weeks pregnancy 0.052 0.018 0.004
Prepregnancy BMI (kg/m2) 0.015 0.002 1.1 x10−17
CD8 + T Cells 0.417 0.220 0.058
CD4 + T Cells 1.069 0.226 2.8 x 10 −6
Granulocytes 0.325 0.143 0.024

Model summary R2 = 0.24