Table 4.
Associations of peripheral blood DNA methylation of MIS2, RAPH1 and SLC25A10 with concurrent BMI in mothers of RAINE adolescents. Associations are adjusted for maternal age. BMI and maternal age were ascertained at the time of blood collection. Total sample size is 406. All β-coefficients are expressed per SD change of CpG. q-values which pass FDR accounting for multiple testing are shown in darker font.
| Outcome | Gene | CpG | β | P value | FDR q-value |
|---|---|---|---|---|---|
| BMI# | MSI2 | CpG1 | 0.031 | 3.60E-04 | 0.0017 |
| CpG2 | 0.044 | 1.20E-04 | 0.0008 | ||
| CpG3 | 0.043 | 1.80E-05 | 0.0003 | ||
| SLC25A10 | CpG1 | 0.018 | 0.1 | 0.1370 | |
| CpG2 | 0.018 | 0.11 | 0.1429 |