TABLE 3.

Hazard ratios of death for patients aged 0–39 years, diagnosed with diffuse large B-cell lymphoma, during 2001–2014 in California

	Univariable HR (95% CI)	Adjusted HR (95% CI)a
Age at diagnosis, years
0–19	Reference	Reference
20–39	2.04 (0.99–4.19)	1.94 (0.91–4.12)
Period of diagnosis
2001–2007	Reference	Reference
2008–2014	0.53 (0.35–0.81)	0.71 (0.45–1.12)
Sex
Male	Reference	Reference
Female	0.65 (0.43–0.99)	0.95 (0.60–1.50)
Race/ethnicity
Non-Hispanic white	Reference	Reference
Non-Hispanic black	1.60 (0.86–2.98)	0.92 (0.46–1.83)
Hispanic	2.03 (1.32–3.13)	1.44 (0.90–2.32)
Asian/Pacific Islander	0.49 (0.26–0.94)	0.75 (0.39–1.45)
Other/unknown	0.57 (0.08–4.16)	0.62 (0.08–4.63)
Stage at diagnosis
Localized	Reference	Reference
Regional	1.05 (0.57–1.94)	1.04 (0.56–1.96)
Advanced	3.09 (1.92–4.96)	2.47 (1.50–4.05)
Unknown	2.74 (0.65–11.63)	1.47 (0.32–6.71)
Rituximab use
No	Reference	Reference
Yes	0.57 (0.38–0.84)	0.56 (0.37–0.85)
Unknown	0.54 (0.17–1.76)	0.58 (0.17–1.93)
Treatment at an NCI-designated cancer center
No	Reference	Reference
Yes	0.96 (0.63–1.46)	1.12 (0.72–1.74)
Neighborhood SES (quintiles)
First (low)	2.37 (1.23–4.57)	1.11 (0.55–2.25)
Second	1.48 (0.75–2.92)	1.15 (0.57–2.34)
Third	1.66 (1.00–2.76)	1.36 (0.79–2.36)
Fourth	1.24 (0.74–2.08)	1.21 (0.71–2.05)
Fifth (high)	Reference	Reference
Health insurance
Private	Reference	Reference
No insurance	2.25 (1.25–4.06)	1.89 (1.03–3.46)
Publicb	2.67 (1.77–4.03)	1.43 (0.90–2.26)
Unknown	1.22 (0.30–5.00)	1.47 (0.35–6.25)
HIV status
Negative	Reference	Reference
Positive	5.73 (3.91–8.40)	3.48 (2.20–5.50)

Abbreviations: CI, confidence interval; HIV, human immunodeficiency virus; HR, hazard ratio; NCI, National Cancer Institute; SES, socioeconomic status.

^aAdjusted for all variables in the table.

^bIncludes Medicaid, Medicare, or Military insurance.