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. 2022 Aug 22;2022:5936753. doi: 10.1155/2022/5936753

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Copyright © 2022 Rongzhou Li et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

XAV939 reversed TRIM50 knockdown-promoted GC cell proliferation and metastasis. Cell proliferation, cycle progression, migration, and invasion in transfected GC cells treated with or without 10 µmol/l of XAV939 were assessed with CCK-8 (a), flow cytometry assay (b), scratch assay (c), and Transwell assay (d) after 48 h of transfection. One-way ANOVA and Tukey tests were applied for multi-group comparison. ^▲p < 0.05 and ^▲▲p < 0.01vs. Vector or shNC. ^∗p < 0.05 and ^∗∗p < 0.01vs. shNC + XAV939. Results were presented as mean ± SD. n = 3.