Table 1.
Basic clinical characteristics of all patients and diabetic patients.
| Variable | All patients (N =309) | Diabetes status | t/H value | P valuea | |
|---|---|---|---|---|---|
| Without diabetes (N =168) | With diabetes (N =141) | ||||
| Age (years) | 57.86 ± 15.10 | 54.12 ± 17.11 | 62.31 ± 10.75 | 16.686 | <0.001 |
| BMI (kg/m2) | 23.88 (21.33, 25.52) | 23.36 (20.70, 24.90) | 24.70 (22.34, 25.93) | 10.579 | 0.001 |
| Follow-up time (m) | 25.67 (12.45, 37.02) | 28.55 (18.81, 39.38) | 23.90 (9.42, 33.62) | 9.183 | 0.002 |
| eGFR at first (mL/min/1.73m2) | 33.56 (24.11, 45.63) | 34.14 (25.56, 45.47) | 32.55 (20.63, 45.83) | 4.596 | 0.032 |
| CR at first (μmol/L) | 185.05 ± 61.78 | 177.38 ± 50.46 | 194.19 ± 72.15 | -2.401 | 0.017 |
| Urea nitrogen (mmol/L) | 11.00 (7.70, 13.86) | 10.23 (7.45, 13.23) | 11.40 (8.06.14.45) | 5.389 | 0.020 |
| Hemoglobin (g/L) | 107.74 ± 22.60 | 113.66 ± 22.28 | 100.68 ± 20.96 | 5.239 | <0.001 |
| Serum albumin (g/L) | 35.20 (29.75, 39.20) | 36.80 (31.90, 39.80) | 34.00 (28.75, 37.60) | 7.593 | 0.006 |
| Uric acid (μmol/L) | 431.82 ± 102.42 | 430.56 ± 100.26 | 433.32 ± 105.27 | -0.236 | 0.814 |
| ALP (U/L) | 68.00 (55.00, 87.00) | 67.00 (55.00, 84.00) | 71.00 (56.50, 91.00) | 2.323 | 0.128 |
| Triglyceride (mmol/L) | 2.04 (1.33, 4.21) | 1.84 (1.29, 4.20) | 2.14 (1.37, 4.24) | 1.129 | 0.288 |
| LDL (mmol/L) | 2.83 (1.95, 3.71) | 2.91 (2.16, 3.70) | 2.71 (1.83, 3.72) | 1.771 | 0.183 |
| Calcium (mmol/L) | 2.16 (2.04, 2.26) | 2.16 (2.06, 2.26) | 2.16 (2.01, 2.26) | 0.072 | 0.789 |
| Phosphorus (mmol/L) | 1.22 (1.09, 1.39) | 1.20 (1.06, 1.34) | 1.26 (1.12, 1.45) | 4.483 | 0.034 |
| Potassium (mmol/L) | 4.29 ± 0.64 | 4.28 ± 0.62 | 4.31 ± 0.67 | -0.419 | 0.676 |
| Bicarbonate (mmol/L) | 23.68 ± 3.51 | 23.47 ± 3.37 | 23.92 ± 3.67 | -1.120 | 0.263 |
| ACR (mg/g) | 1064.39 (448.82, 3522.24) | 1166.46 (282.99, 2477.71) | 2327.14 (766.48, 4152.06) | 11.667 | 0.001 |
| HbA1c (%) | 6.20 (5.50,7.20) | 5.75 (5.47,6.40) | 7.20 (6.30,8.50) | -6.636 | <0.001 |
| eGFR at end point (mL/min/1.73m2) | 19.05 (8.20, 40.56) | 23.45 (11.74,47.20) | 12.42 (6.60,25.08) | 4.658 | 0.001 |
| CR at end point (μmol/L) | 391.2 ± 290.8 | 351.4 ± 288.4 | 473.5 ± 279.6 | -3.512 | 0.001 |
Abbreviations: BMI: body mass index; CR: creatinine; eGFR: estimated glomerular filtration rate; ALP: alkaline phosphatase; LDL: low-density lipoprotein; ACR: microalbuminuria/urine creatinine; aP-value for comparison across those with and without diabetes. The t test was used to compare the normally distributed variables (serum creatinine, hemoglobin, uric acid, serum potassium, and bicarbonate). The Kruskal-Wallis test was used to compare the non-normally distributed variables (age, BMI, follow-up time, eGFR, urea nitrogen, serum albumin, uric albumin, ALP, triglyceride, LDL, serum calcium, and serum phosphorus).