Table 3.
15 mCRC-EV-miRs associated with mCRC detection and therapeutic response
| Gene ID | r (Pearson's correlation) | p-value (Pearson's correlation) | ROC (mCRC) | Fold change (pre vs. HC) | P-value (fold change) |
|---|---|---|---|---|---|
| EV-miR-320c | 0.593 | 1.1735E-06 | 0.896 | 6.3 | 5.2644E-08 |
| EV-miR-4516 | 0.579 | 2.3759E-06 | 0.939 | 10.8 | 3.7395E-05 |
| EV-miR-320b | 0.558 | 6.6156E-06 | 0.743 | 2.4 | 0.0004 |
| EV-miR-552-3p | 0.499 | 7.9085E-05 | 0.683 | 6.0 | 0.0014 |
| EV-miR-4488 | 0.470 | 0.0002 | 0.946 | 112.8 | 4.9997E-07 |
| EV-miR-200b-5p | 0.422 | 0.001 | 0.717 | 8.4 | 0.0012 |
| EV-miR-193a-5p | 0.421 | 0.001 | 0.894 | 2.8 | 1.6426E-05 |
| EV-miR-4664-3p | 0.383 | 0.003 | 0.742 | 11.2 | 0.0025 |
| EV-miR-141-3p | 0.341 | 0.010 | 0.779 | 11.3 | 0.0003 |
| EV-miR-1307-3p | 0.323 | 0.014 | 0.831 | 2.3 | 9.0321E-05 |
| EV-miR-194-5p | 0.313 | 0.018 | 0.943 | 3.9 | 8.6146E-09 |
| EV-miR-200c-3p | 0.303 | 0.022 | 0.954 | 11.7 | 8.8483E-06 |
| EV-miR-29a-3p | 0.277 | 0.037 | 0.769 | 2.2 | 0.0017 |
| EV-miR-222-3p | 0.270 | 0.042 | 0.750 | 2.1 | 0.0022 |
| EV-miR-24-3p | 0.269 | 0.043 | 0.841 | 2.1 | 1.4288E-05 |