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. 2022 Oct 5;32(10):469–475. doi: 10.2188/jea.JE20210393

Table 4. HRsa and 95% CIs of mortality associated with amount of consuming either American or White ginseng among individuals who consumed ginseng for perceived general benefit for enhancement of health, Shanghai Women’s Health Study.

Cause of deaths Never Use
(N = 41,431)
Amount of ginseng use, grams/year

<375
(N = 4,270)
375–749.99
(N = 5,095)
≥750
(N = 3,557)
P-trend
All causes
Deaths (N) 3,427 466 603 368 0.017
HR (95% CI) 1.00 0.86 (0.78–0.94) 0.93 (0.85–1.01) 0.92 (0.82–1.03)
Cardiovascular diseases
Deaths (N) 1,049 160 197 147 0.989
HR (95% CI) 1.00 0.82 (0.69–0.97) 0.89 (0.76–1.03) 1.15 (0.96–1.38)
Cancer
Deaths (N) 1,551 216 247 148 0.110
HR (95% CI) 1.00 1.01 (0.88–1.17) 0.95 (0.83–1.09) 0.87 (0.72–1.02)
Other causes
Deaths (N) 827 90 159 73 0.005
HR (95% CI) 1.00 0.64 (0.51–0.80) 0.95 (0.80–1.12) 0.71 (0.55–0.91)

CI, confidence interval, HR, hazard ratio.

aAdjustment: age, income, marriage status, education, menopause status, comorbidity (hypertension, diabetes), exercise, waist-to-hip ratio, body mass index, diet, vitamin and calcium supplements.

All HRs and 95% CI are calculated compared with never users.