Fig. 3.

Excisional biopsy and GCOC histological features (H&E* staining): A High power showed malignant cellular features with areas of necrosis surrounded by large pleomorphic cells demonstrating vesicular nuclei; B & C Large bizarre looking cells and abnormal mitotic figures; D areas of dentinoid deposits; E sheets of ghost cell keratinization; F intravascular invasion; G tumor cells encroaching on nerve fiber. H The medial margin was positive for tumor islands invasion into the nasal septum; I COC-like area of cystic space lined with delicate odontogenic epithelium formed of basal ameloblast-like cells and an upper layer of stellate reticulum-like cells with ghost cell keratinization. (*Hematoxylin and eosin)