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. 2022 Aug 16;13:961668. doi: 10.3389/fgene.2022.961668

FIGURE 7.

FIGURE 7

Circ_0096442 promotes proliferation and migration/invasion of A549 cells in bone microenvironment. (A) RT-qPCR detection showing the expression of circ_0096442 in overexpression and knockdown stable A549 cells. (B) Cell proliferation was detected by CCK8 assays. (C) Cell proliferation was detected by colony formation assays. (D) Transwell assays were applied to discover the migration/invasion ability of A549 cells in bone microenvironment. (E) Apoptosis assay by flow cytometric analysis. (F) Western blot analysis for the detection of pro-apoptotic and anti-apoptotic proteins. (G) Impact of circ_0096442 on A549 cellular migration assessed through wound healing assays.