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. 2022 Aug 18;36:103152. doi: 10.1016/j.nicl.2022.103152

Table 3.

Number of datasets included in final analysis, quantitative quality metrics and voxel tissue fractions. HERMES data quality for GABA+ and GSH subspectra was assessed by SNR, linewidth and fit error. PRESS data quality assessed using the tNAA signal for SNR, linewidth and CRLBs. Data quality and voxel tissue composition did not differ significantly between groups with the exception of ACC GABA+ SNR (t(49) = 2.21, p = 0.032) which was higher in PPCS participants than controls. SNR: signal-to-noise ratio. fGM/fWM/fCSF are the voxel fractions of GM, WM and CSF.

Anterior cingulate cortex
Right sensorimotor cortex
Control PPCS Control PPCS
scanned 29 28 29 28
retained 26 25 27 28
GABA+ SNR 10.73 ± 1.77 11.90 ± 2.02 15.28 ± 2.63 15.55 ± 2.80
GABA+ FWHM 23.93 ± 3.58 24.14 ± 3.31 21.96 ± 1.90 21.68 ± 1.14
GABA+ fit error 9.86 ± 3.71 8.90 ± 3.22 5.83 ± 1.87 5.88 ± 2.10
scanned 29 28 29 28
retained 25 27 26 27
GSH SNR 17.61 ± 4.21 18.22 ± 3.66 9.07 ± 2.81 8.06 ± 1.64
GSH FWHM 14.61 ± 2.51 14.21 ± 3.04 11.72 ± 3.99 11.63 ± 3.59
GSH fit error 9.40 ± 2.85 10.49 ± 3.51 10.92 ± 3.42 10.45 ± 2.92
scanned 29 29 29 29
retained 29 29 29 29
tNAA SNR 134.15 ± 19.29 134.37 ± 18.83 158.28 ± 21.31 156.55 ± 24.72
tNAA FWHM 12.50 ± 3.06 12.41 ± 3.11 8.74 ± 3.76 9.96 ± 3.21
tNAA CRLB 2.14 ± 0.58 2.10 ± 0.31 1.24 ± 0.44 1.31 ± 0.47
fGM 0.477 ± 0.033 0.469 ± 0.030 0.324 ± 0.032 0.331 ± 0.036
fWM 0.347 ± 0.051 0.362 ± 0.046 0.598 ± 0.042 0.591 ± 0.046
fCSF 0.176 ± 0.043 0.169 ± 0.048 0.078 ± 0.027 0.079 ± 0.031