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. 2022 Aug 16;9:986943. doi: 10.3389/fnut.2022.986943

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Copyright © 2022 Lv, Huang, Li, Gong, Sun, Mao and Guo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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POAE and POEE reduced the number of immune cells and abnormal increase in serum Ig E in AD mice. (A) Spleen indices of mice in each group (n = 5 per group). (B–F) The number of lymphocytes, eosinophils, basophils, monocytes and neutrophils in each group of mice (n = 5 per group). (G) Pictures of representative dorsal skin TB staining of each group. Red circles mark some of the mast cells (Scale bar: 200 μm). (H) The number of mast cells in the dermis of each group (n = 3 per group). (I) Serum Ig E concentration of mice in each group (n = 3 per group). The data were expressed as mean ± SD. ^##P < 0.01, ^###P < 0.001, ^####P < 0.0001, vs. control groups; *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, vs. model (DNCB) groups.