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POAE and POEE inhibit skin lesions and pruritus-associated cytokines in AD mice. (A) Skin His concentrations in each group of mice. (B) Skin Il-31 concentrations in each group of mice. (C–H) Relative mRNA expression of Ifn-γ, Tnf-α, Tslp, Il-4, Flg, and Lor in each group of mice. The data were expressed as mean ± SD (n = 3 per group). #P < 0.05, ##P < 0.01, ###P < 0.001, vs. control groups; *P < 0.05, **P < 0.01, ***P < 0.001, vs. model (DNCB) groups.
