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. 2022 Aug 16;13:979939. doi: 10.3389/fphar.2022.979939

FIGURE. 7.

FIGURE. 7

Z1456467176 inhibits NLRP3 inflammasome activation in rat model of gout. (A) ELISA of serum IL-1β levels in the four groups. (B) qPCR of IL-1β gene levels in the peripheral whole blood cells of rats in each group. (C) WB of NLRP3, p20, and IL-1β expression in the joints and surrounding synovial tissues of rats in each group. Data are presented as the means ± S.E.M.s. Statistics were analyzed using Dunnett’s t test. n = 4. *p < 0.05; **p < 0.01.