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. 2022 Jul 22;11(4):673–682. doi: 10.1093/toxres/tfac043

Fig. 2.

Fig. 2

TAM increased lipid synthesis and liver lipid uptake, decreased TG export in HFD rat liver. A) the protein expression of p-SREBP1c, m-SREBP1c, and HMGCR were investigated by western blot. B) The protein expression of SCD1 and ELOVL6 were investigated by western blot. C) The protein expressions of ACC, p-ACC, and FAS were investigated by western blot. D) The protein expressions of CD36, MTTP, and LDLR were investigated by western blot. Band intensity was quantified by densitometry analysis. The rats were treated with TAM (4, 8 mg/kg) intragastrically or not after CD or HFD for 15 weeks. The results are the mean ± SEM (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001 compared to the CD-control group. #P < 0.05, ##P < .01, ###P < 0.001 compared to the HFD-control group.