Fig. 3.

Pin1 overexpression attenuates arsenic-induced cytotoxicity in L02 cells. (A) Representative images of PIN1 protein expression after Pin1 plasmid transfection in the different treatment groups. (B) Semiquantification of PIN1 protein levels after Pin1 plasmid transfection in the different treatment groups. (C) Pin1 plasmid transfection ameliorated the arsenic-induced morphological damage, as observed under a light microscope at 10× magnification. (D) Pin1 plasmid transfection inhibited the arsenic-induced decline in cell viability. The data are presented as the mean ± SEM of four independent experiments. ^*P < .05, ^**P < .01 vs. the control group. ^#P < .05, ^##P < .01 vs. the arsenic group.