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. 2022 Aug 16;13:918071. doi: 10.3389/fphar.2022.918071

TABLE 1.

The traditional and modern prescriptions of S. nigrum in China.

Preparation name Composition Route of administration Dosage form Indications for use References
Longkui san S. Nigrum , Hylotelephium erythrostictum (Miq.) H. Ohba, Coptis chinensis Franch., Os Draconis (FossiliaOssiaMastodi), Boswellia carterii Birdw., Momordica cochinchinensis (Lour.) Spreng., Abelmoschus manihot (Linn.) Medicus External use Making into powder Malignant sores Sheng Ji Zong Lu” (Song Dynasty, A.D. 1117)
Longkui san S. Nigrum , Boswellia carterii Birdw., Prunus armeniaca L., Coptis chinensis Franch External use Making into powder Malignant sores Sheng Ji Zong Lu” (Song Dynasty, A.D. 1117)
Longkuigeng san S. Nigrum , Moschus berezovskii Flerov External use Making into powder Back sore Sheng Ji Zong Lu” (Song Dynasty, A.D. 1117)
Longkui gao S. Nigrum , Hyoscyamus niger Linn., Allium sativum L., Coriandrum sativum Linn., Prunus armeniaca L. External use Making into cream Malignant prickling sore pain Tai Ping Sheng Hui Fang” (Song Dynasty, A.D. 992)
Xinlikang capsules Scutellaria barbata D. Don, S. Nigrum , Duchesnea indica (Andr.) Focke, Astragalus membranaceus (Fisch.)Bge., Panax ginseng C. A. Meyer, Saussurea involucrata (Kar. et Kir.) Sch.-Bip., Angelica sinensis (Oliv.) Diels, Curcuma longa Linn., Salvia miltiorrhiza Bunge Take orally Decocting with water, and then making into granules Invigorate qi and nourish blood, remove blood stasis and detoxify, cancer Liu et al. (2019a)
Compound Tianxian capsules Trichosanthes kirilowii Maxim., Clematis chinensis Osbeck, Hedyotis diffusa Willd., Bos taurus domesticus Gmelin, S. Nigrum , Arisaema heterophyllum Blume, Boswellia carterii Birdw., Commiphora myrrha (Nees) Engl., Panax ginseng C. A. Meyer, Astragalus membranaceus (Fisch. )Bge., Polyporus umbellatus (Pers.) Fr., Elphe taeniura Cope, Cinnamomum camphora (L. ) Presl, Moschus berezovskii Flervo Take orally Making into capsules Supervened after esophageal cancer and stomach cancer, peptic ulcer Kang et al. (2014)
Loulian capsules Hedyotis diffusa Willd., Semiaquilegia adoxoides (DC.) Makino, Polygonum onrientale L., Paris polyphylla Smith. var. yunnanensis (Franch.) Hand.-Mzt., Amyda sinensis (Wiegmann), Curcuma zedoaria (Christm.) Rosc., Lobelia chinensis Lour., Steleophaga Plancyi (Boleny), Whitmania pigra Whitman, Panax ginseng C. A. Meyer, Fallopia multiflora (Thunb.) Harald., S. Nigrum Take orally Making into capsules Hepatitis, liver cirrhosis, liver cancer, breast cancer, hemangioma Zhang, (2015)
Baiying qinghou decoction Solanum lyratum Thunberg, S. Nigrum , Duchesnea indica (Andr.) Focke, Scutellaria barbata D. Don, Armeniaca mume Sieb Take orally Decocting with water Laryngeal cancer Qiu Yuan Ying Fang
Kaizhi longgu san Os draconis (FossiliaOssiaMastodi), Asarum sieboldii Miq., Gypsum Fibrosum, Ligusticum sinense Oliv., S. Nigrum , Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook. f., Gypsum Rubrum, Salt External use Making into powder Bad breath Pu Ji Fang” (Ming Dynasty, A.D. 1390)
Lingxian longcao decoction Clematis chinensis Osbeck, S. Nigrum , Prunella vulgaris Linn., Smilax glabra Roxb., Trichosanthes kirilowii Maxim., Clematis terniflora DC., Iphigenia indica Kunth, Wikstroemia indica (Linn.) C. A. Mey Take orally Decocting with water Phlegm scrofula, breast mass, wheezing, vomiting Yan Fang Xuan Bian” (A.D. 1959)