Table 3.
Cox proportional-hazards regression model for multivariate analysis in the PSM.
| HR | 95% CI | P-value | ||
|---|---|---|---|---|
| Recurrence-free Survival | ||||
| Sex | Male vs. Female | 1.223 | 0.802-1.867 | 0.349 |
| Smoking history | Current vs. never | 0.961 | 0.499-1.745 | 0.291 |
| Age (years) | ≤65 vs. >65 | 0.847 | 0.553-1.298 | 0.447 |
| Vascular invasion | Present vs. absent | 4.399 | 2.907-6.659 | < 0.001 |
| Pleural invasion | Present vs. absent | 2.056 | 1.213-3.484 | 0.007 |
| Lymphatic invasion | Present vs. absent | 1.298 | 0.824-2.044 | 0.261 |
| Pathologic stage | 0.262 | |||
| StageIA2 | Stage IA2 vs. Stage IB | 0.599 | 0.213-2.440 | 0.599 |
| StageIA3 | Stage IA3 vs. Stage IB | 1.520 | 0.830-2.782 | 0.175 |
| StageIB | Stage IB vs. Stage IB | 1.000 | ||
| Adjuvant therapy | Absent vs. present | 1.810 | 1.184-2.766 | 0.006 |
| Overall Survival | ||||
| Sex | Male vs. Female | 1.152 | 0.717-1.849 | 0.558 |
| Smoking history | Current vs. never | 0.867 | 0.641-1.945 | 0.508 |
| Age (years) | ≤ 65 vs. >65 | 0.299 | 0.483-1.250 | 0.777 |
| Vascular invasion | Present vs. absent | 5.014 | 3.154-7.969 | < 0.001 |
| Pleural invasion | Present vs. absent | 2.086 | 1.162 -3.743 | 0.014 |
| Lymphatic invasion | Present vs. absent | 1.711 | 1.052-2.784 | 0.045 |
| Pathologic stage | 0.652 | |||
| StageIA2 | StageIA2 vs. Stage IB | 0.861 | 0.249-2.980 | 0.813 |
| StageIA3 | StageIA3 vs. Stage IB | 1.326 | 0.659-2.667 | 0.429 |
| StageIB | Stage IB vs. Stage IB | 1.000 | ||
| Adjuvant therapy | Absent vs. present | 1.675 | 1.043-2.689 | 0.033 |