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. 2022 Aug 16;12:956270. doi: 10.3389/fonc.2022.956270

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Copyright © 2022 Makutani, Kawakami, Tsujikawa, Yoshimura, Chiba, Ito, Kawamura, Haratani and Nakagawa

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Prognostic impact of MMP14-expressing cells. (A) Percentage of MMP14-expressing cells among cell subsets as determined by mIHC analysis. Each dot represents one patient, and the median value and interquartile range are shown for each plot. (B) Kaplan-Meier curves for RFS according to the median values of the MMP14⁺ CAF/CAF ratio (left) or the MMP14⁺ tumor cell/tumor cell ratio (right).