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. 2021 Sep 28;19(8):1211–1223. doi: 10.20892/j.issn.2095-3941.2020.0294

Figure 1.

Figure 1

Vermurafenib resistant melanoma cells exhibited more invasiveness and invadopodia formation. (A) Quantitation of the invaded cells in vemurafenib resistant WM793 cells cultured with and without vemurafenib (n = 3). (B, C) Representative images of actin fluorescence staining showing invadopodia (B) and quantification of invadopodia (C) in naïve and vermurafenib resistant WM793 cells (n = 3). (D) Quantitation of invadopodia at indicated times after 10% fetal bovine serum stimulation in naive and vermurafenib resistant WM793 cells (n = 3). Scale bars = 10 μm. *P < 0.05; **P < 0.01; ***P < 0.001.