Table 1.
Isolates and transconjugants | Date of isolation | Specimen | Hospital/private laboratory | Ward | Plasmid-mediated blaAmpC | Other β-lactamases genes | PMQRs genes | MICs (mg/L) |
RAPD clone | MLST (K. pneumoniae) | Replicon typing | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AMX | AMC | TZP | CTX | CAZ | ATM | FEP | IMP | FOX | |||||||||||
K. pneumoniae 47 | 04/04/2007 | Urine | AWH | Surgery | CMY-4 | TEM-1 | – | >256 | 48 | >256 | >32 | >256 | 32 | <04 | 0.38 | 64 | K.A. | 17 | Inc A/C, LVPK |
TC47 | CMY-4 | – | >256 | 16 | 128 | >32 | 128 | 32 | <04 | 0.19 | 32 | Inc A/C | |||||||
K. pneumoniae 123 | 04/05/2005 | Urine | AWH | Pediatrics | CMY-4 | TEM-1 | – | >256 | 32 | >256 | >32 | >256 | 32 | >64 | 0.38 | 64 | K.B. | 1617 | Inc A/C, FIB, F, P |
TC123 | CMY-4 | – | >256 | 16 | 16 | 12 | 12 | <04 | <04 | 0.25 | 32 | Inc A/C | |||||||
K. pneumoniae 613 | 05/04/2010 | Feces | AZH | Medicine | CMY-4 | – | >256 | 16 | 08 | >32 | 192 | 32 | <04 | 0.25 | 64 | K.D. | 1618 | ND | |
K. pneumoniae 615 | 03/05/2010 | Feces | AZH | Medicine | CMY-4 | – | >256 | 16 | 08 | >32 | 192 | 32 | <04 | 0.25 | 64 | K.D. | 1618 | ND | |
K. pneumoniae 413 | 21/04/2008 | Feces | AZH | Surgery | DHA-1 | TEM-1; CTX-M-3; SHV-12 | QnrB4 | >256 | 16 | 02 | >32 | 48 | 32 | 16 | 0.19 | 16 | K.C. | 834 | Inc L/M, LVPK, HI2 |
TC413 | DHA-1 | TEM-1 | QnrB4, acc(6)-Ib | >256 | 02 | 0.38 | 0.19 | 03 | <04 | <04 | 0.032 | 16 | Inc LVPK | ||||||
E. coli 234 | 15/04/2007 | Urine | AZH | Surgery | CMY-4 | TEM-1; CTX-M-15 | – | >256 | 32 | >256 | >32 | >256 | 32 | >64 | 0.5 | 64 | E.A. | Inc A/C, F, P, FII2K | |
TC234 | CMY-4 | – | >256 | 16 | 12 | >32 | 96 | 32 | <04 | 0.25 | 64 | Inc A/C | |||||||
E. coli 412 | 22/04/2008 | Feces | AZH | Pediatrics | CMY-4 | TEM-1 | – | >256 | 32 | >256 | >32 | >256 | 32 | <04 | 0.5 | 32 | E.B. | Inc A/C, FIA, A/C, FIB, F, B/O, U | |
TC412 | CMY-4 | – | >256 | 16 | >256 | >32 | 48 | 32 | <04 | 0.25 | 32 | Inc A/C, | |||||||
E. coli 535 | 14/04/2009 | Urine | LPL | Community | CMY-4 | TEM-1 | – | >256 | 16 | 16 | >32 | >256 | 32 | <04 | 0.25 | 64 | E.C. | Inc A/C, FIB, HI1 | |
E. coli 538 | 14/02/2009 | Urine | LPL | Community | CMY-4 | TEM-1 | – | >256 | 16 | 08 | >32 | 128 | 32 | <04 | 0.19 | 64 | E.D. | Inc A/C, FIB, FIA, FII 1K, U | |
TC538 | LPL | CMY-4 | – | >256 | 16 | 04 | >32 | 64 | 32 | <04 | 0.19 | 32 | Inc A/C | ||||||
E. coli 539 | 05/04/2009 | Urine | LPL | Community | CMY-4 | TEM-1 | – | >256 | 16 | 16 | >32 | >256 | 32 | <04 | 0.25 | 64 | E.C. | Inc A/C, FIB, HI1 | |
E. coli 545 | 24/02/2009 | Urine | LPL | Community | CMY-4 | TEM-1 | – | >256 | 16 | 08 | >32 | 128 | 32 | <04 | 0.19 | 64 | E.D. | Inc A/C, FIB, FIA, FII 1K, U | |
E. coli 560 | 01/12/2009 | Urine | LPL | Community | CMY-4 | TEM-1 | – | >256 | 16 | 08 | >32 | 128 | 32 | <04 | 0.19 | 64 | E.D. | Inc A/C, FIB, FIA, FII 1K, U | |
E. coli 606 | 21/04/2010 | Urine | DPL | Community | CMY-4 | TEM-1 | – | >256 | 16 | 04 | >32 | 48 | 08 | <04 | 0.19 | 32 | E.E. | ND | |
E. coli 611 | 28/05/2010 | Feces | AZH | Surgery | CMY-4 | TEM-1, CTX-M-15 | – | >256 | 16 | 04 | >32 | 64 | 32 | 16 | 0.25 | 64 | E.F. | Inc FIA, I1, F, U, FII 1K | |
TC611 | CMY-4 | – | >256 | 16 | 02 | >32 | 08 | 32 | <04 | 0.25 | 32 | Inc A/C | |||||||
P. mirabilis 128 | 07/04/2005 | Urine | AZH | Surgery | CMY-4 | TEM-1 | – | >256 | 48 | 12 | >32 | 48 | <04 | <04 | 0.25 | 32 | – | Inc A/C | |
TC128 | CMY-4 | – | >256 | 16 | 0.75 | >32 | 24 | <04 | <04 | 0.25 | 32 | Inc A/C |
LPL, Lalaoui private laboratory; DPL, Djama private laboratory; AZH, Amizour hospital; AWH, Amriw hospital; TZP, piepracillin–tazobactam; AMX, amoxicillin; AMC, amoxicillin–clavulanic acid; FOX, cefoxitin; ATM, aztreonam; CTX, cefotaxime; CAZ, ceftazidime; FEP, cefepime; IMP, imipenem; ND, not determined.