Figure 4.

Comparisons of mutation frequencies between patients with vitreoretinal lymphoma and primary central nervous system lymphoma. (A) The frequencies of the most prevalent mutations in patients with vitreoretinal lymphoma and primary central nervous system lymphoma are shown in the bar plot. *P<0.1; **P<0.05; ***P<0.01. (B) The locations of the mutations in the IRF4 gene are shown. Each patient is represented by a color, as indicated in the legend. The mutations detected in the baseline samples are represented by circles, while stars represent the mutations that were only detected in the post-treatment samples. VRL: vitreoretinal lymphoma; PCNSL: primary central nervous system lymphoma.