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. 2015 Jan 27;19(2):209–212. doi: 10.1016/j.bjid.2014.12.007

Table 1.

Comparison of variables from recent case series of S. bovis infective endocarditis.

A B C D E F G H I J
Brazil France France France Germany Italy Italy Spain Spain Ireland
Study period 2005–2014 1980–1991 1987–1992 1993–2001 1983–1996 1990–2003 1990–2003 1988–2005 1997–2008 2000–2009
Number of S. bovis IE 9 53 32 40 22 22 30 55 16 7
% number S. bovis/total IE 9/201 (4%) 53/482 (11%) N/D 40/206 (19%) 22/265 (8%) N/D 30/199 (15%) 55/228 (24%) N/D N/D
Age average (standard deviation) 56.7 (13.4) 60.6 (12.2) 61.3 (5) 64 (12) 67 (range 49–76) 59.5 58.6 (12.4) 66 69.5 (11.8) 70.9 (8.6)
Male, n (%) 7 (77.7%) 42 (79.2%) 27 (84%) 34 (85%) 12 (54%) 17 (77.6%) 17 (77.2%) 51 (93%) 9 (56.3%) 5 (71.4%)
Female, n (%) 2 (22.3) 11 (20.8%) 5 (15%) 6 (15%) 10 (46%) 5 (22.4%) 5 (22.8%) 4 (7%) 7 (43.6%) 2 (28.6%)



Site of infection
 Native mitral valve 0 (0%) 6 (11%) N/D 7 (17%) N/D 3 (13%) 4 (13%) 10 (18%) N/D 1/7 (14%)
 Native aortic valve 6 (66.6%) 26 (49%) N/D 15 (37%) N/D 9 (26%) 8 (27%) 22 (40%) N/D 0 (0%)
 Native mitro-aortic valves 2 (22.2%) 18 (33%) N/D N/D N/D 7 (40%) 12 (40%) 23 (42%) N/D 1/7 (14%)
 Prosthetic valve 0 (0%) 0 (0%) N/D 5 (12%) N/D 2 (10.0%) 3 (10%) 0 (0%) 10/16 (62.5%) 3/7 (43%)
 Tricuspid valve 0 (0%) 1 (1.8%) N/D 2 (5%) N/D 1 (6.7%) 2 (7%) 0 (0%) N/D 0 (0%)



Clinical aspects
 Heart failure 1 (11.1%) 35/53 (66%) ND 8/40 (20%) 7/22 (32%) ND 12 (40%) 15 (27%) ND 2 (28.6%)
 Embolism 2/6 (33.3%) 22/53 (42%) ND 22 (55%) 2/22 (9%) ND ND 21 (38%) 2 (13%) 0
 Surgery 6 (66.6%) 41/53 (77%) ND 22 (55%) 16/22 (73%) ND 22 (73%) 19 (29%) 6 (38%) 2 (28.6%)



Colonoscopy
 Patients with colonoscopy 9 (100%) 40/53 (75%) 32/32 40/40 ND 18/22 (82%) 27/30 (90%) 46/55 (84%) 15/16 (94%) 7 (100%)
 Patients with positive colonoscopy 7 (77.7%) 27 (67%) 18 (56.2%) 22 (56%) ND 8 (%) 4 (15%) 29 (63%) 14 (93.0%) 6 (85.7%)



In-hospital mortality 0 (0%) 4 (7.5%) N/D 1 (2%) ND ND 5 (16.7%) 12 (22%) 2 (12.5%) 0 (0%)

A – present study, adapted from references: B – Ballet et al. (1995); C – Bruno Hoen et al. (1994); D – Pergola et al. (2001); E – Kupferwasser et al. (1998); F – Tripodi et al. (2005); G – Tripodi et al. (2004); H – Corredoira et al. (2008); I – Fernández-Ruiz et al. (2010); J – Fitzmauric et al. (2013).