Table 2.
Details of ERBB2 single nucleotide polymorphisms (SNPs) genotyped in the three populations.
| SNP rs# | Location (Build Hg19) | Cohorts genotyped | Minor allele | Minor allele frequency (Pará/RN/Bahia) | Position/function |
|---|---|---|---|---|---|
| rs2517955 | 37843931 | RN/Bahia | C | 0.49/0.41 | Upstream region |
| rs2517956a | 37844109 | Pará/RN/Bahia | G | 0.38/0.38/0.42 | Upstream region |
| rs1810132 | 37866255 | RN/Bahia | C | 0.39/0.40 | Intronic |
| rs2952156a | 37877085 | Pará/RN/Bahia | A | 0.38/0.38/0.38 | Intronic |
| rs1136201a | 37879838 | RN/Bahia | G | 0.15/0.12 | Coding, non-syn (I655V) |
Note. Cohorts are from Pará, RN and Bahia states in northeastern Brazil.
a
SNPs associated with leprosy in Pará.
Adapted from Araújo et al.6