Table 1.
Risk factors for early-onset neonatal healthcare associated infection (EOHCAI) – univariate analysis.
| Variable | EOHCAI N = 283 (50.4%) |
Without EOHCAI N = 278 (49.6%) |
Relative risk | p-value |
|---|---|---|---|---|
| Male gender | 148 (52) | 152 (55) | 0.95 | 0.57 |
| Gestational age at birth – weeks | 34.00 (3.79) | 36.56 (3.42) | <0.01 | |
| Mean (SDa) | ||||
| Birth weight (g) | ||||
| >1500 | 202 (71) | 255 (91) | ||
| 1000–1500 | 52 (18) | 16 (5) | ||
| <1000 | 29 (10) | 7 (2) | <0.01 | |
| PROM >18 h | 95 (33) | 168 (60) | 1.94 | <0.01 |
| APGAR <5 on 5th min | 19 (6) | 19 (6) | 0.98 | 0.97 |
| Vaginal delivery | 119 (42) | 115 (41) | 1.02 | 0.94 |
| Neonatal Surgery | 6 (2) | 6 (2) | 1.0 | 0.97 |
| Antenatal care | 259 (91) | 262 (94) | 0.96 | 0.21 |
| Fewer than antenatal visits | 182 (64) | 113 (40) | 1.62 | <0.01 |
| Number of pregnancies (including the studied) | 1.11 (1.38) | 1.06 (1.40) | 0.66 | |
| Mean (SDa) | ||||
| Parity (including the studied) | 1.11 (1.38) | 1.06 (1.40) | 0.66 | |
| Mean (SDa) | ||||
| Previous prematurity | 40 (14) | 29 (10) | 1.4 | 0.24 |
| Previous natimortality | 13 (5) | 15 (7) | 0.86 | 0.70 |
| Hypertension on pregnancy | 65 (23) | 71 (25) | 0.88 | 0.48 |
| Sexually transmitted infections in pregnancy | 7 (2) | 9 (3) | 0.76 | 0.58 |
| Infections in pregnancy | 93 (33) | 85(31) | 1.07 | 0.50 |
| Tobacco exposure in pregnancy | 45(16) | 41(15) | 1.08 | 0.69 |
| Alcohol exposure in pregnancy | 25(9) | 25(9) | 0.98 | 0.55 |
| Antibiotic use on antenatal care | 77 (27) | 81(29) | 0.93 | 0.68 |
| Complication during delivery | 221 (78) | 135 (49) | 1.59 | <0.01 |
| Antibiotic use in labor/delivery | 183(64) | 149(53) | 1.22 | <0.01 |
| Invasive procedures in the mother at the admission | 8(3) | 1(0.3) | 8.0 | <0.01 |
| Maternal infection at the admission | 78 (27) | 27 (10) | 2.7 | <0.01 |
| Maternal age in years | 26.36 (7.14) | 25.95 (6.60) | 0.47 | |
| Mean (SDa) | ||||
| Born in Unit 1 | 138 (48) | 65 (23) | 2.0 | <0.01 |
a
Standard deviation.