. 2016 Nov 4;21(1):35–41. doi: 10.1016/j.bjid.2016.09.007

Table 1.

Patients characteristics, CD4 count, plasma DNA damage marker 8-OHdG, and serum carbonyl content.

Group	Subgroup	Male/female	Age (mean)	CD4 (mean)	Time on anti-retroviral therapy (mean)	8-OHdG	Carbonyl content
		count	years	cells/μL	months	ng/mL	nmol/mg of protein
HIV-negative controls	20–40 yrs	87/63	34.8 ± 5.1	NA	NA	1.07 ± 0.25	0.64 ± 0.08
HIV-negative controls	40–60 yrs	92/58	47.3 ± 5.4	NA	NA	1.30 ± 0.32	0.66 ± 0.10

HIV-infected ART naive	20–40 yrs	28/22	31.6 ± 4.2^b	624 ± 202^b	NA	1.81 ± 0.66^a	0.76 ± 0.13^a
HIV-infected ART naive	40–60 yrs	33/17	45.2 ± 6.1^b	602 ± 134^b	NA	1.95 ± 0.56^a	0.77 ± 0.18^a

HIV-infected on first line ART	20–40 yrs	30/20	34.3 ± 5.2^b	502 ± 233^b	63.6^a	2.50 ± 0.91^a	1.06 ± 0.31^a
HIV-infected on first line ART	40–60 yrs	41/9	48.3 ± 4.8^b	465 ± 165^b	65.7^a	3.13 ± 0.92^a	1.08 ± 0.37^a

HIV-infected on second line ART	20–40 yrs	36/14	35.6 ± 4.3^b	400 ± 144^b	74.3^a	2.79 ± 0.95^a	1.20 ± 0.36^a
HIV-infected on second line ART	40–60 yrs	43/7	47.5 ± 5.3^b	376 ± 183^b	76.8^a	3.27 ± 0.99^a	1.22 ± 0.36^a

Values are mean ± SEM of subjects. The data were analyzed by one-way ANOVA.

p < 0.01 significant when compared to control.

p < 0.05 significant when compared to control.