Table 5.
Recommendations of antimicrobials for pediatric patients in OPAT in Brazil.a
| Antimicrobial | Dose and posology for normal renal and hepatic functions |
|---|---|
| Amikacin | 15 mg/kg once a day |
| Gentamicin | 7 mg/kg once a day |
| Cefepime | 50 mg/kg/dose twice a day |
| Ceftaroline | 35–45 mg/kg in 3 doses Maximum dose 1200 mg/day |
| Ceftazidime | 50 mg/kg/dose twice a day |
| Ceftriaxone | 50 mg/kg once a day For meningitis, 50 mg/kg/dose twice a day |
| Ertapenem | 15 mg/kg/dose twice a day |
| Meropenem | 40 mg/kg/dose twice a day |
| Vancomycin | 15 mg/kg/dose twice a day |
| Teicoplanin | 6 mg/kg once a day |
| Daptomycin | There is no standardization |
| Linezolid | 10 mg/kg/dose twice a day |
| Tigecycline | There is no standardization |
| Anidulafungin | There is no standardization |
| Caspofungin | 50 mg/m2 once a day |
| Micafungin | There is no standardization |
| Voriconazole | 4 mg/kg/dose twice a day |
| Amphotericin B (lipid complex) | 5 mg/kg once a day |
| Amphotericin B (liposomal) | 3–5 mg/kg once a day |
OPAT, outpatient parenteral antimicrobial therapy.
a
For children over 28 days old.