Table 1.

Risk factors analysis for ventilator-associated pneumonia caused by Carbapenem-resistant Enterobacteriaceae.

Continuous variables	Death		Survival		p-Value
	(n = 64)		(n = 48)
	Meana	SDc	Mean	SD
Age	61.7	19.0	45.9	19.6	<0.001f
ICU total admission	14.1	11.1	15.9	28.5	0.657
VM days	14.1	11.1	15.2	28.4	0.781
Total admission (days)	30.3	16.6	70.9	81.1	<0.001f
Days before VAP	19.0	13.0	18.1	28.6	0.826
Days after VAP	11.3	9.4	52.8	59.5	<0.001f
Charlson index	2.1	2.5	0.8	1.6	0.003f
APACHE	26.1	5.5	26.5	4.7	0.702

Categorical variables	nb	%	n	%	p-Value
Gender (male)	39	60.9%	35	72.9%	0.109
Burn	2	3.1%	4	8.3%	0.209
HIV infection	1	1.6%	1	2.1%	0.671
Diabetes	10	15.6%	3	6.3%	0.122
Diabetes with complications	6	9.4%	2	4.2%	0.257
Chronic renal failure	8	12.5%	1	2.1%	0.046f
Previous myocardial infarction	9	14.1%	6	12.5%	0.533
Congestive heart failure	7	10.9%	2	4.2%	0.177
Peripheral artery disease	2	3.1%	0	0.0%	0.329
Previous stroke	10	15.6%	3	6.3%	0.122
Previous stroke with plegia	1	1.6%	1	2.1%	0.671
Dementia	3	4.7%	2	4.2%	0.641
COPD	4	6.3%	2	4.2%	0.492
Hypertension	31	48.4%	12	25.0%	0.011f
Neoplasm	9	14.1%	1	2.1%	0.028f
Lymphoma	1	1.6%	0	0.0%	0.575
Leukemia	0	0.0%	0	0.0%	–
Metastatic tumor	5	7.8%	0	0.0%	0.059
Rheumatic disease	2	3.1%	1	2.1%	0.613
Peptic ulcer	0	0.0%	0	0.0%	–
Hepatic disease	2	3.1%	1	2.1%	0.613
Cirrhosis	0	0.0%	1	2.1%	0.425
Chronic corticoid use	3	4.7%	0	0.0%	0.187
Other immunosuppressants	6	9.4%	1	2.1%	0.121
Trauma on admission	26	40.6%	28	58.3%	0.041f
Elective surgery	7	10.9%	5	10.4%	0.692
Emergency surgery	32	50.0%	29	60.4%	0.162

Treatment	nb	%	n	%	p-Value
Incorrect treatment<24 h	45	70.3%	36	75.0%	0.390
Correct treatment <24 hd	19	29.7%	12	25.0%	0.390
Incorrect treatment <5 days	18	28.1%	11	22.9%	0.298
Correct treatment<5 days	46	71.9%	37	77.1%	0.298
Monotherapyd	40	62.5%	26	54.2%	0.276
Combined therapye	6	9.4%	11	22.9%	0.044f

^aMean of total deaths or survival.

^bNumber of cases.

^cStandard deviation.

^dAt least one active drug.

^eAt least two active drugs.

^fp < 0.05.