Table 2.
Patient and Disease Characteristics
| Variable | Brazil (n = 199) |
|---|---|
| Age, mean (SD) | 52.0 (5.7) |
| Male, n (%) | 128 (64.3) |
| Caucasian, n (%) | 92 (46.2) |
| At least one comorbidity, N (%) | 155 (77.9) |
| Diabetes | 76 (49.0) |
| Coronary artery disease (incl. myocardial infarction, coronary artery bypass graft, etc.) | 43 (27.7) |
| Peripheral vascular disease | 29 (18.7) |
| Chronic pulmonary disease | 23 (14.8) |
| Congestive heart failure | 21 (13.5) |
| Other Comorbidity | 17 (11.0) |
| Diabetes with end organ damage | 15 (9.7) |
| Mild liver disease | 12 (7.7) |
| Primary reason for hospitalization is treatment of MRSA cSSTI, n (%) | 153 (80.1) |
| Type of cSSTI, n (%) | |
| Deep/extensive cellulitis | 57 (28.6) |
| Infected burn | 9 (4.5) |
| Infected ulcer | 35 (17.6) |
| Major abscess | 26 (13.1) |
| Posttraumatic wound infection | 17 (8.5) |
| Surgical site infection | 55 (27.6) |
| Source of cSSTI, n (%) | |
| Community acquired | 117 (58.8) |
| Healthcare-associated (prior hospitalization in the past 90 days, residence in a nursing home or extended care facility | 32 (16.1) |
| Hospital acquired (>48 h after admission) | 35 (17.6) |
| Unknown/not documented | 15 (7.5) |
| MRSA infection within 12 months prior to hospitalization, n (%) | 11 (5.5%) |
| Surgical procedure related to cSSTI treatment, n (%) | 52 (26.1) |
| Incision/drainage | 28 (53.8) |
| Debridement | 21 (40.4) |
| Othera | 2 (3.8) |
| Revascularization | 2 (3.8) |
| Closure of wound | 1 (1.9) |
| Removal of prosthesis | 1 (1.9) |
| Infections during hospitalization, n (%) | |
| IV-line infection | 5 (2.5) |
| Super infection | 10 (5.0) |
| Severe sepsis or septic shock | 51 (25.6) |
Abbreviations: cSSTI, complicated skin and soft tissue infection; h, hour; incl, include; IV, intravenous; MRSA, methicillin-resistant Staphylococcus aureus; SD, standard deviation.
a
Other = skin grafting, resection.