Skip to main content
. 2022 Aug 30;61(10):1331–1343. doi: 10.1007/s40262-022-01170-x
In vitro studies have demonstrated that nafamostat mesylate has antiviral activity and appears to be one of the most potent drugs against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).
Clinical trials to date are limited but suggest a potential benefit of nafamostat in patients with severe coronavirus disease 2019 (COVID-19).
Current evidence from case reports and observational studies provides guidance for potential adverse effects.