Table 5.

In Vivo Confocal Microscopy Cornea Findings as Described in Various Types of Mucopolysaccharidosis

Type	Corneal features on in vivo confocal microscopy
MPS IV (Stewart S et al.[28])	Normal corneal epithelium and sub-basal nerves.
	Anterior and mid-stroma show diffuse, irregular hyperreflectivity. Keratocyte cytoplasm has a granular appearance and rounded nuclei with vacuoles, concentrated in the posterior stroma.
	Endothelium is unaffected.
MPS I-S (Grupcheva CN et al.[29])	Basal epithelium contains brightly appearing cells.
	Keratocytes in mid stroma appear round or elliptical and with well-defined hyporeflective centers.
	Anterior Descemet layer contains hyperreflective, round bodies.
MPS VI	Epithelium and Bowman’s layer is unaffected.
(Patel DV et al.[30])	Keratocytes with different shapes and hyporeflective regions occupy posterior stromal layers.
	Endothelium is unaffected.