Table 2.
Genes that are common to various IRDs after the analysis of genes from Retnet database using Venn diagram for overlapping genes for various diseases
IRDs | Common genes |
---|---|
RP and macular degeneration | BEST1, FSCN2, GUCA1B, IMPG1, ABCA4, PROM1, RP1L1 |
RP and LCA | CRX, IMPDH1, RDH12, RPE65, CRB1, IFT140, LRAT, SPATA7, TULP1 |
RP, LCA, and MD | PRPH2 |
LCA and MD | OTX2 |
US and other retinopathy | ADGRV1, ARSG, CDH23, CEP250, CEP78, CIB2, DFNB31, ESPN, MYO7A, PCDH15, USH1C, USH1G |
SDR, US, retinopathy | ABHD12, HARS |
RP, SDR | ADIPOR1, CWC27, HGSNAT, IFT140, TRNT1, OFD1 |
RP and retinopathy | BEST1, KIF3B, NR2E3, CRB1, CYP4V2, MVK, RGR, PLBP1, ZNF408 |
RP, US, retinopathy | CLRN1, USH2A |
RP and BBS | ADIPOR1, ARL6, BBS1, BBS2, IFT172, TTC8 |
RP and CCRD | SEMA4A, ABCA4, CERKL, PROM1 |
RP, CCRD, CSNB | CRX, PRPH2 |
RP, CSNB | RDH12, RPE65, SAG, CRB1, IFT140, LRAT, SPATA7, TULP1 |
RP, BBS, and CCRD | C8orf37 |
BBS, CSNB | KCNJ13 |
BBS=Bardet–Biedl syndrome, autosomal recessive, CCRD=cone or cone–rod dystrophy, CSNB=congenital stationary night blindness, IRD=inherited retinal disease, LCA=Leber congenital amaurosis, MD=macular degeneration, RP=retinitis pigmentosa, SD=syndromic/systemic diseases with retinopathy, US=Usher syndrome