Table 1.
Comparison of clinical and ocular biometric characteristics between nanophthalmos (NO) group and control (CO) group
| NO group | CO group | P a | |
|---|---|---|---|
| Number of subjects | 40 | 30 | - |
| Age, years | 8.95 (4.0) | 10.47 (3.0) | 0.089 |
| Female gender, n (%) | 22 (55.0) | 14 (46.7) | 0.490b |
| UCVA, logMAR | |||
| Median (Snellen’s equivalent) | 1.18 (4/60) | 0 (6/6) | <0.001c |
| IQR | 1.08 to 1.48 | 0 to 0 | |
| BCVA, logMAR | |||
| Median (Snellen’s equivalent) | 0.60 (6/24) | 0 (6/6) | <0.001c |
| IQR | 0.30 to 0.78 | 0 to 0 | |
| Spherical equivalent, D | 10.87 (3.1) | 0.19 (0.7) | <0.001 |
| Axial length, mm | 16.67 (1.3) | 22.91 (0.9) | <0.001 |
| ACD, mm | 2.50 (0.3) | 3.47 (0.3) | <0.001 |
| Lens thickness, mm | 3.64 (0.5) | 3.36 (0.2) | 0.005 |
| CCT, mm | 537.90 (43.1) | 542.57 (31.4) | 0.713 |
| RCS thickness, mm | 2.01 (0.2) | 1.52 (0.1) | <0.001 |
| Keratometry, D | |||
| Kf | 48.56 (2.4) | 43.52 (1.3) | <0.001 |
| Ks | 49.51 (2.2) | 44.58 (1.7) | <0.001 |
| Astigmatism | 1.03 (0.5) | 1.09 (0.7) | 0.785 |
| Lens axial length factor | 2.19 (0.3) | 1.47 (0.1) | <0.001 |
| LT/ACD | 1.47 (0.2) | 0.97 (0.1) | <0.001 |
UCVA, uncorrected visual acuity; BCVA, best-corrected visual acuity; Kf, keratometry in flat meridian; Ks, keratometry in steep meridian; LAF, lens axial length factor=LT/AXL ×10; ACD, anterior chamber depth; RCS, retinochoroidal scleral thickness; CCT, central corneal thickness; IQR, interquartile range; logMAR, logarithm of minimal angle of resolution. aIndependent t-test; bChi-square test/Fisher’s exact test; cMann-Whitney U test