TABLE 2.
Frequency-specific gFCD alternations in the VA group.
| Frequency band | Contrast | Cluster regions | L/R | Cluster size | MNI coordinates | Z-score | ||
| x | y | z | ||||||
| Full low frequency | Post > Pre | – | ||||||
| Pre > Post | HIP | L | 20 | 0 | –63 | 48 | 3.63 | |
| HIP/PHG | R | 36 | 27 | –30 | –18 | 3.44 | ||
| Slow-5 | Post > Pre | ACC | R | 26 | 9 | 42 | 9 | 3.36 |
| DLPFC | R | 20 | 33 | 24 | 45 | 3.73 | ||
| aIFG | R | 32 | 51 | 39 | 9 | 3.63 | ||
| Pre > Post | HIP | L | 43 | –15 | –33 | –6 | 3.52 | |
| HIP | R | 30 | 36 | –27 | –15 | 3.22 | ||
| SMA/MCC | R | 26 | 12 | –12 | 48 | 3.54 | ||
| Slow-4 | Post > Pre | S2 | L | 59 | –54 | –6 | 39 | 3.46 |
| S2 | R | 58 | 63 | 3 | 18 | 3.30 | ||
| Pre > Post | – | |||||||
| Slow-3 | Post > Pre | aINS | L | 37 | –39 | 12 | 3 | 4.07 |
| aINS | R | 22 | 39 | 30 | –3 | 3.05 | ||
| pINS | L | 148 | –51 | –6 | 3 | 4.09 | ||
| pINS | R | 162 | 69 | –3 | 9 | 3.76 | ||
| Pre > Post | PCU | L | 34 | –9 | –66 | 51 | 3.52 | |
Voxel level, p < 0.005, cluster level, p < 0.05, cluster size > 20 voxels; the small volume correction was applied in case the pain-related brain regions (cluster size less than or equal to 20) were not significant by FWE test. HIP, Hippocampus; PHG, Parahippocampal Gyrus; ACC, Anterior Cingulate Cortex; DLPFC, Dorsolateral Prefrontal Cortex; aIFG, Anterior Inferior Frontal Gyrus; SMA, Supplementary Motor Area; MCC, Middle Cingulate Cortex; S2, Second Somatosensory Cortex; aINS, Anterior Insula; pINS, Posterior insula; PCU, Precuneus.