TABLE 1.
Description of the population with chronic HBV infection diagnosis 1990–2015 in Sweden, n = 16,410 (coinfection with HCV excluded)
| Western Europe | Eastern Europe | Middle East–North Africa | Sub‐Saharan Africa | East/Southeast Asia | Other | |
|---|---|---|---|---|---|---|
| HBV population (%) | 2316 (14.1) | 2349 (14.3) | 4402 (26.8) | 3677 (22.4) | 3537 (21.6) | 129 (0.8) |
| Women (%) | 903 (39) | 1139 (48) | 1843 (42) | 1510 (41) | 2273 (64) | 56 (43) |
| Birth year a (IQR) | 1958 (1947–1977) | 1969 (1956–1981) | 1970 (1961–1979) | 1976 (1967–1985) | 1975 (1966–1982) | 1968 (1958–1978) |
| Deceased (%) | 462 (20.0) | 177 (7.5) | 203 (4.6) | 79 (2.1) | 103 (2.9) | 10 (7.7) |
| Immigration year a (IQR) | 1979 c (1970–1998) | 1994 (1991–2003) | 1995 (1988–2007) | 2005 (1995–2010) | 2000 (1990–2007) | 1996 (1988–2006) |
| Age a at immigration (IQR) | 23.6 c (17.1–29.9) | 27.0 (19.2–34.9) | 25.9 (18.6–34.2) | 26.8 (18.3–33.7) | 25.5 (15.2–32.0) | 27.7 (21.2–34.3) |
| Years b in Sweden | NA c | 19.4 | 18.6 | 11.6 | 16.8 | 18.6 |
| HBV diagnosis year a (IQR) | 2002 (1997–2007) | 2003 (1997–2009) | 2004 (1998–2010) | 2007 (2001–2012) | 2006 (1999–2010) | 2004 (1999–2009) |
| Age a in years at HBV diagnosis (IQR) | 42 (26–56) | 34 (25–45) | 33 (25–42) | 30 (22–38) | 31 (24–37) | 36 (27–45) |
| HDV coinfection d (%) | 8 (0.3) | 19 (0.8) | 84 (1.9) | 46 (1.3) | 42 (1.2) | 1 (0.8) |
| HIV coinfection d (%) | 55 (2.4) | 4 (0.2) | 7 (0.2) | 97 (2.6) | 46 (1.3) | 7 (5.4) |
| HBV treatment (%) | 228 (9.8) | 195 (8.3) | 460 (10.5) | 181 (4.9) | 530 (15.0) | 9 (7.0) |
| Serious liver disease/cirrhosis (%) | 128 (5.5) | 73 (3.1) | 118 (2.7) | 35 (1.0) | 71 (2.0) | 5 (3.9) |
| Liver transplant (%) | 25 (1.1) | 15 (0.6) | 41 (0.9) | 6 (0.2) | 10 (0.3) | 1 (0.8) |
| HCC (%) | 49 (2.1) | 45 (1.9) | 58 (1.3) | 23 (0.6) | 54 (1.5) | 3 (2.3) |
| Age in years b at HCC diagnosis | 61.3 | 61.0 | 59.2 | 44.7 | 51.0 | 54.5 |
| Total in statistical analyses | ||||||
| n = 16,352 (%) | 2293 (14.0) | 2343 (14.3) | 4390 (26.8) | 3673 (22.5) | 3525 (21.6) | 128 (0.8) |
| Observation time, all, person years | 25,415 | 26,237 | 47,320 | 30,565 | 35,358 | 1177 |
| Observation time, men, person years | 15,406 | 13,704 | 25,544 | 17,008 | 12,614 | 526 |
| Observation time, years, mean/person | 11.1 | 11.2 | 10.8 | 8.3 | 10.0 | 9.2 |
| HCC in analyses (%) | 34 (1.5) | 40 (1.7) | 47 (1.0) | 17 (0.5) | 43 (1.2) | 2 (1.6) |
Abbreviations: HBV, hepatitis B virus; HCC, hepatocellular carcinoma; HCV, hepatitis C virus; HDV, hepatitis D virus; HIV, human immunodeficiency virus; IQR, interquartile range; NA, not available.
a
Median.
b
Mean.
c
28% immigrants (72% from Sweden).
d
Eight HCC in HDV coinfected, two HCC in HIV coinfected.