TABLE 2.

Characteristics of SNPs in HFC‐PRS and East Asian NAFLD‐PRS in the SCHS

CHR	SNP	Position (hg19)	Gene	Minor allele	Major allele	MAF Overall	MAF among cases	MAF among non‐cases	CHISQ	p
HFC‐PRS (n = 24,333, 208 HCC cases)
2	rs1260326	chr2:27730940	GCKR	T	C	0.47	0.51	0.47	3.86	0.145
19	rs58542926	chr19:19379549	TM6SF2	T	C	0.07	0.12	0.07	63.65	<0.001
19	rs641738	chr19:54676763	MBOAT7	T	C	0.25	0.27	0.25	1.46	0.483
22	rs738409	chr22:44324727	PNPLA3	G	C	0.37	0.45	0.37	12.41	0.002
East Asian NAFLD‐PRS (n = 24,294, 206 HCC cases)
2	rs1260326	chr2:27730940	GCKR	T	C	0.47	0.51	0.47	3.57	0.167
19	rs4808199	chr19:19545099	GATAD2A	A	G	0.31	0.34	0.31	2.07	0.355
22	rs2896019	chr22:44333694	PNPLA3	G	T	0.38	0.45	0.38	9.35	0.009

Note: p value significance is for the chi‐square statistical test.

Abbreviations: CHR, chromosome; CHISQ, chi‐square statistic; MAF, minor allele frequency; SNP, single nucleotide polymorphism.