FIG 5.

Fungal catalase production during coinfection. (A) Mean LFQ intensity for two C. neoformans catalase proteins identified by proteomic profiling; (B) normalized zone of inhibition measurements by H₂O₂ plate assays. Data were normalized to the C. neoformans WT. (C) H₂O₂ plate assays across conditions. Data were normalized to C. neoformans WT. Statistical analysis using Student's t test: *, P < 0.05; **, P < 0.001. Images were taken 48 h after incubation at 37°C with 10% H₂O₂. The experiment was performed in biological quadruplicate and technical duplicate.