Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mpro mutation breakdown at nirmatrelvir contact and catalytic residues. (A) Mutations identified at residues directly interacting with nirmatrelvir and/or substrate peptide. (B) Three-dimensional structural model of Mpro (PDB ID 7RFS), with residues from panel A highlighted in “stick” representation and shown in individual colors. The protein backbone is shown in ribbon representation. AA, amino acid. Stop codons are donoted as (*).
