TABLE 5.

Content analysis of written communications used to return negative results to participants across studies

	1	2	3	4	5	6	7	8	9	10
Reminder of study participation	✓	✓	✓	✓	✓	✓	✓	✓	✓	✓
Purpose of letter	✓	✓	✓	✓	✓	✓	✓	✓	✓
Limitations of negative results	✓	✓	✓	✓	✓	✓	✓	✓	✓
Contact information for study team	✓		✓	✓	✓	✓	✓	✓	✓	✓
Confirmation that genomic testing was completed	✓	✓	✓	✓	✓		✓	✓
Encouragement to speak with a genetic counselor and/or their PCP about their result	✓			✓	✓	✓		✓	✓
Reminder that participants consented to receive result		✓	✓	✓			✓
Encouragement to speak with family members about their result				✓	✓
Relevance of their result for family member									✓

Note: Written communications analyzed here include materials used to return results (letters and messages used to return results via the patient portal). Ancillary materials were not included in this analysis.