Table 3.
Recommendations for the harmonious generation of omic datasets towards the goals of advancing mechanistic knowledge and clinical translation in IBD research.
Policy domain | Stakeholders | Recommendations |
---|---|---|
Funding and resource allocation | • Funding agencies • IBD consortia • Principal investigators |
• Prolonged funding for generating omic datasets from IBD patients in a longitudinal manner • Targeted financial support for promoting international collaboration with research stakeholders in developing countries • ‘Follow-up’ grants to generate missing particular omic datasets to complement pre-existing omic datasets from the same samples • Ring-fencing funding for training skilled omic scientists |
Collaboration and harmonisation | • Funding agencies • Principal investigators • Non-profit medical organisations in the realm of IBD • IBD consortia • Principal investigators |
• Compilation of commonly agreed standards for IBD omic datasets • Coordinated strategies between international and national funders to avoid huge redundancies in terms of omic datasets • Creation of an easily shareable IBD omic dataset catalog between multiple funders and agencies in the IBD domain • Encouraging exchange programmes for interdisciplinary research |
Legal and organisational | • Universities • Principal investigators • Industry |
• Creating robust and flexible inter-institutional confidentiality agreements to promote exchange of knowledge and information while fulfilling GDPR requirements • Intra- and inter-project alignment for achieving multiple objectives using the same omic datasets |
GDPR, general data protection regulation; IBD, inflammatory bowel disease.