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. Author manuscript; available in PMC: 2022 Aug 30.
Published in final edited form as: Curr Psychopharmacol. 2021 Jan 8;11(1):11–17. doi: 10.2174/2211556009666210108112737

Fig. (1). Dopaminylation in Cocaine Use and Withdrawal.

Fig. (1).

Illustrates how histone arginine dopaminylation that occurs in psychostimulant abuse is combated by H3R2me2a binding inhibitor Srcin1 and during withdrawal and normalizes dopamine expression at the Nucleus Accumbens (NAc) and like the major DRD2 A2 allelic polymorphism is protective against psychostimulant seeking behavior. DA = Dopamine.